Tr is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

作用机制：

It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. Tr was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake, 4 and reduce body weight in patients with type 2 diabetes.

潜在的研究应用

食欲控制和饱腹感研究

血糖和胰岛素敏感性研究

肥胖和代谢综合征模型

GLP-1受体途径调节研究

Tr mechanism of action: effects on endocrine function and insulin resistance in patients with type 2 diabetes. Tr is a novel glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 (GLP-1) receptor agonist approved in the United States as an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes. It is under investigation for use in chronic weight management, major adverse cardiovascular events, and the management of other conditions, including heart failure with preserved ejection fraction, obesity, and non-cirrhotic non-alcoholic steatohepatitis. The Phase 3 SURPASS 1-5 clinical trial programme was designed to assess the efficacy and safety of once-weekly subcutaneously injected tir (5, 10, and 15 mg), as monotherapy or combination therapy, across a broad spectrum of people with type 2 diabetes.

Use of tir in clinical studies was associated with marked reductions in glycated haemoglobin (-1.87 to -2.59%, -20 to -28 mmol/mol) and body weight (-6.2 to -12.9 kg), as well as reductions in parameters commonly associated with heightened cardiometabolic risk such as blood pressure, visceral adiposity, and circulating triglycerides. In SURPASS-2, these reductions were greater than those with the GLP-1 receptor agonist se1 mg. Tir was well tolerated, with a low risk of hypoglycaemia when used without insulin or insulin secretagogues, and showed a generally similar safety profile to the GLP-1 receptor agonist class. Accordingly, evidence from these clinical trials suggests that tir offers a new opportunity for the effective lowering of glycated haemoglobin and body weight in adults with type 2 diabetes.

产品展示

分析报告

客户反馈

工厂介绍

Shanghai Rise & Shine New Materials Co. LTDisa national high-tech enterprise deeply rooted in the biopolypeptide sector, specializing in the R&D, production, sales, and full-chain services of peptide products. We are committed to empowering the health and beauty industries with independent innovative technologies.

核心定位与使命:

We focus on the core biopolypeptide track and build a complete industrial chain from raw material R&D to end-user applications, covering diverse scenarios such as pharmaceuticals, functional foods and health products, and cosmetics.

秉承“技术自主、品质第一”的理念，以“让生物肽造福更多人”为使命，努力将“中国肽”推向全球市场。

质量控制与市场布局

我们严格执行全面的质量管理体系：从原材料采购、生产过程到产品检验的每一个环节都受到严格控制，确保产品的高质量和稳定性。

全球市场布局：我们的产品销往多个国家和地区，赢得了全球客户的广泛认可和信任。

坚持“质量第一、客户至上”的原则：以客户需求为中心，提供个性化产品定制和解决方案，满足多样化需求。

If you′re looking for a reliable and effective solution to support your weight management journey, Shanghai Rise & Shine New Materials Co. LTD is your trusted partner. Contact us today to learn more about our products and how they can help you achieve your goals.

包装及运输

常问问题

Q1: 产品的订购流程是怎样的？

A: 请告诉我们您需要的具体产品规格和数量。然后告诉我们您的交货信息。付款成功后我们会尽快为您安排付款并发货给您。

Q2: 我可以订购的最低金额是多少？

A: 我们可以订购的最小数量是 1 盒，其中包含 10 瓶。

Q3: 我什么时候可以收到包裹？

答：付款后会尽快发货，发货时间一般为7至15天。

Q4: 你们会提供样品来测试质量吗？

A: 是的，运费由客户承担。